Chinese Journal of Nature ›› 2015, Vol. 37 ›› Issue (4): 287-296.doi: 10.3969/j.issn.0253-9608.2015.04.007

• History of Natural Science • Previous Articles     Next Articles

The establishment of homologous recombination mechanisms

XIANG Yihe   

  1. Department of Physics, Tsinghua University, Beijing 100084, China
  • Received:2014-09-12 Online:2015-08-25 Published:2015-09-16

Abstract: The establishment of homologous recombination mechanisms is introduced. The key events include the discover of gene linkage and recombination phenomena, the proposition of chiasmatype hypothesis, the appear of breakage, reunion and copy choice hypothesis, the establishment of three models of homologous recombination: Holliday model, single-strand-break and double-strandbreak repair model for recombination.