Abstract: In the last half of century, with the swift development of brain science, deeper insight into memory, emotion, consciousness and even free will have got much knowledges, thus questions about how reliable the testimony by eyewitnesses and the confession of the suspects is, new technology to collect evidences, and even if there is free will or people should be responsible for their actions, are raised from new angles of view. Some interdisciplinary fields such as neurolaw and forensic neuroscience have been emerging, a radical reform of the main principles underlying the law is on its way.