History of Natural Science

The establishment of homologous recombination mechanisms

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  • Department of Physics, Tsinghua University, Beijing 100084, China

Received date: 2014-09-12

  Online published: 2015-09-16

Abstract

The establishment of homologous recombination mechanisms is introduced. The key events include the discover of gene linkage and recombination phenomena, the proposition of chiasmatype hypothesis, the appear of breakage, reunion and copy choice hypothesis, the establishment of three models of homologous recombination: Holliday model, single-strand-break and double-strandbreak repair model for recombination.

Cite this article

XIANG Yihe . The establishment of homologous recombination mechanisms[J]. Chinese Journal of Nature, 2015 , 37(4) : 287 -296 . DOI: 10.3969/j.issn.0253-9608.2015.04.007

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