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    Historical review and current development of artificial intelligence
    GU Xianfeng
    Chinese Journal of Nature    2016, 38 (3): 157-166.   DOI: 10.3969/j.issn.0253-9608.2016.03.001
    Abstract4888)      PDF(pc) (2102KB)(6684)       Save

    This work gives a brief review of the history of artificial intelligence, and analyzes the current status of the field. The main principles and methodologies of the major branches in AI included symbolism and connectionism. Furthermore, the history, and booming reasons and major applications of deep learning are introduced as well.

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    Cited: Baidu(4)
    Use of artificial intelligence in disease prediction
    XU Liang, RUAN Xiaowen, LI Xian, HONG Boran, XIAO Jing
    Chinese Journal of Nature    2018, 40 (5): 349-354.   DOI: 10.3969/j.issn.0253-9608.2018.05.004
    Abstract2926)      PDF(pc) (989KB)(2496)       Save

    This work introduces the application status and prospect of artificial intelligence in disease prediction comprising two aspects: public health prevention and control, personal disease screening and health management. The drawbacks of traditional methods for disease prevention and control are analyzed. The breakthroughs and developments of disease prediction brought by artificial intelligence are summarized in view of data sources and techniques. Finally, this work gives some examples of the productions of disease prediction by artificial intelligence.

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    On artificial intelligence spatial analysis
    ZHENG Minrui,ZHENG Xinqi,WANG Jiao
    Chinese Journal of Nature    2018, 40 (5): 363-372.   DOI: 10.3969/j.issn.0253-9608.2018.05.006
    Abstract3408)      PDF(pc) (2331KB)(891)       Save

    Spatial analysis is a method of quantitative analysis of spatial phenomena, which becomes the core competitiveness of supporting the development of GIS. Especially with the rapid development of smart phones, mobile payment systems and shared bicycles, spatial analysis has been brought to a new stage of artificial intelligence in just a few years. In order to draw a blueprint for the coming artificial intelligence spatial analysis (AISA), this paper first briefly combs the key nodes of the development of spatial analysis: the computerized work mode from 0 to 1, global visual calculation, hidden LBS and intelligent applications, cloud GIS and
    artificial intelligence spatial-temporal decision-making. Secondly, the five schools of machine learning, the evolution characteristics of dominant algorithms and spatial analysis are summarized. Thirdly, the definition, modeling principles and technical framework of AISA are proposed. Finally, several hot area of AISA in the future are proposed, such as intelligent spatial computing, hyperparametric spatial optimization, intelligent spatial planning robot, full-sample spatial-temporal prediction and spatial neural network analysis. By combing, analyzing, summarizing and predicting the history and trend of artificial inerlligence spatial analysis, this paper aims to provide systematic theoretical and applied data for artificial intelligence spatial analysis.

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    Developing artificial intelligence with a down-to-earth approach
    GUO Yike
    Chinese Journal of Nature    2019, 41 (2): 79-84.   DOI: 10.3969/j.issn.0253-9608.2019.02.001
    Abstract1333)      PDF(pc) (2247KB)(737)       Save

    Today, artificial intelligence has been significant progress. The breakthrough development of machine learning has promoted the adaptation of artificial intelligence with a wide range of applications. Artificial intelligence become a new highland for the development of science and technology in the world, and all countries have made strategic investment. At the same time, the development of artificial intelligence has also presented us with a new challenge, introducing new topics in our ethics and social governance. While looking forward to the bright future of artificial intelligence, we must also clearly recognize the limitation of current state-of-the-art in artificial intelligence, especially machine learning. The basic methods and basic ideas are relatively still simple and rough. Today’s artificial intelligence is mainly focusing on the emulation of external function of the human intelligence. The development of artificial intelligence still needs to be continuously progressed in the understanding of the intelligent connotation. This article addresses the approaches for future development of artificial intelligence, especially the direction of machine learning research by emphasising a knowledge support and data driven methodology.

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    Quantum artificial intelligence: Quantum computing and artificial intelligence meet at the best time
    TANG Hao, JIN Xianmin
    Chinese Journal of Nature    2020, 42 (4): 288-294.   DOI: 10.3969/j.issn.0253-9608.2020.04.002
    Abstract3247)      PDF(pc) (2403KB)(2497)       Save
    Quantum artificial intelligence is an emerging interdisciplinary science and technology from the crossover of the field of quantum computing and that of artificial intelligence. During the past decades, quantum computing and artificial intelligence have been through different development processes, and both now demonstrate promising application perspectives that may bring up transformative changes for people’s work and life. We are coming to a good timing for the deep crossover of quantum computing and artificial intelligence, and a perfect stage to embark on for the research of quantum artificial intelligence.
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    Quantum computing and artificial intelligence
    ZHANG Hui, LI Lei, DOU Menghan, FANG Yuan
    Chinese Journal of Nature    2020, 42 (4): 321-330.   DOI: 10.3969/j.issn.0253-9608.2020.04.006
    Abstract3452)      PDF(pc) (2399KB)(4815)       Save
    The main purpose of this paper is to explore some potential applications of quantum computing in artificial intelligence and to review the interactions between quantum theory and artificial intelligence. This paper will introduce some famous and simple quantum algorithms, so that readers can understand the power of quantum computing. In addition, in order to give readers a comprehensive understanding of quantum computing, this paper gives a brief overview of quantum computing. This paper will be a bridge for AI researchers to further explore the links between AI and quantum computing including quantum theory.
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    Computational drug design methods by deep learning algorithms 
    LI Fenglei, HU Qiaoyu, XIONG Ruofan, BAI Fang
    Chinese Journal of Nature    2021, 43 (5): 383-390.   DOI: 10.3969/j.issn.0253-9608.2021.05.009
    Abstract2143)      PDF(pc) (1688KB)(2708)       Save
    Drug design and development is a long term, expensive and high-risk process. The continuous innovation of science and technology, as well as the explosive growth of the biomedical data brings unprecedented opportunities for the applications of deep learning algorithms in biomedical areas to expediate the drug development. In this review, we briefly overview and list the state-ofthe-art deep learning-driven drug design methods for identifying drug targets, molecular generation, ligand-based and structure-based drug design.
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    Application of two-dimensional materials in artificial intelligence
    ZHU Hongwei
    Chinese Journal of Nature    2022, 44 (6): 466-468.   DOI: 10.3969/j.issn.0253-9608.2022.06.006
    Abstract1555)      PDF(pc) (1755KB)(1195)       Save
    Two-dimensional materials are the most preferred candidates for neuromorphic devices with low power consumption, miniaturization and large-scale integration. In this paper, the recent progress, advantages and problems of the application of twodimensional materials in artificial intelligence are briefly reviewed, and future development trends are prospected.
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    Generative artificial intelligence and future materials science
    ZHU Hongwei
    Chinese Journal of Nature    2024, 46 (1): 46-49.   DOI: 10.3969/j.issn.0253-9608.2024.01.005
    Abstract2010)      PDF(pc) (1938KB)(1180)       Save
    Artificial intelligence is a powerful driving force behind the rapid development of data-driven science. This article, using the application of deep learning in materials science as an example, introduces the concept of generative models, and their applications in the discovery of new materials and autonomous laboratories. Generative artificial intelligence not only greatly accelerates the research and development process of materials, but also enhances the transparency and credibility of the entire process, heralding a new era in materials science research.
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    Artificial intelligence in cultural heritage conservation
    CHENG Yuan , HUANG Jizhong, ZHANG Yue, PENG Ningbo
    Chinese Journal of Nature    2024, 46 (4): 261-270.   DOI: 10.3969/j.issn.0253-9608.2024.04.003
    Abstract4857)      PDF(pc) (2449KB)(4674)       Save
    Artificial intelligence (AI) is revolutionizing the field of cultural heritage conservation. This paper comprehensively reviews the current applications of AI in various aspects of cultural heritage conservation. In the field of cultural heritage digitization, AI techniques such as semantic segmentation of laser point clouds have significantly improved the efficiency and accuracy of digitization processes. For cultural heritage recognition and management, deep learning-based image segmentation and knowledge graphs provide support for intelligent management. In the area of cultural heritage monitoring and detection, machine learning can autonomously analyze the condition of cultural heritage from environmental parameters and non-destructive testing data, enabling early warning of deterioration. In virtual restoration and display, AI technologies are optimizing methods and experiences from multiple perspectives, including image processing, geometric reconstruction, and interactive presentation. The results show that AI is fundamentally changing the concepts, methods, and technologies of cultural heritage conservation, significantly improving efficiency and accuracy. This review provides a reference for further exploration of AI-enabled pathways in cultural heritage conservation, contributing to the advancement of technological innovation and the deep integration of cultural heritage conservation with modern technology. 
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    Advances in the application of artificial intelligence in environmental science
    LAO Jiayi, WANG Xiaoyan, SHI Bo, WANG Bin, JIAO Zheng
    Chinese Journal of Nature    2024, 46 (4): 271-280.   DOI: 10.3969/j.issn.0253-9608.2024.04.004
    Abstract1976)      PDF(pc) (1681KB)(4641)       Save
    The rapid development and high efficiency of artificial intelligence (AI) have made it increasingly popular in the field of scientific research. Over the past decade, there has been an exponential growth in the application of AI in environmental science. One of the main advantages of using artificial intelligence is its ability to efficiently analyze and process large amounts of data, which is a crucial issue faced by environmental science research. Therefore, the application of artificial intelligence can greatly promote the development of environmental science and engineering. This paper reviews the latest applications of artificial intelligence in the field of environmental science, discusses its advantages and existing problems, as well as the opportunities and challenges it brings to environmental science.
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    From circuit calculation to artificial intelligence——A computer science perspective on Nobel Prize in Physics awarded to AI scholars
    LI Xiaoqiang
    Chinese Journal of Nature    2024, 46 (6): 435-443.   DOI: 10.3969/j.issn.0253-9608.2024.06.006
    Abstract2765)      PDF(pc) (1500KB)(2455)       Save
    Literally speaking, artificial intelligence and physics are two completely different disciplines. In fact, another name for artificial intelligence is “machine intelligence”, where “machine” refers to electronic computers. In 1946, the electronic computer successfully evolved from a circuit system capable of expressing logical algebra (physics), acquiring computing and storage capabilities that rivaled or even surpassed those of humans, and gradually developed into a new field—computer science. This paper interprets the reasons behind the 2024 Nobel Prize in Physics being awarded to AI scholars from the perspective of computer science, by outlining the nearly 80-year history of the birth of computers.
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    From computer-aided drug design to artificial intelligence-driven drug design
    BIAN Yuemin
    Chinese Journal of Nature    0, (): 1-10.   DOI: 10.3969/j.issn.0253-9608.2025.01.001
    Abstract881)      PDF(pc) (2511KB)(1501)       Save
    The rapid advancement of computational science continues to drive innovation and create opportunities in the field of drug discovery. With the ongoing expansion of data in the life sciences and the iterative improvement of computational hardware, computational chemistry and cheminformatics have become indispensable tools for researchers in preclinical drug design. This article focuses on two key themes — computer-aided drug design (CADD) and artificial intelligence-driven drug design (AIDD) — to provide a concise overview of the interdisciplinary exploration and innovation at the intersection of computational science and drug discovery, as well as the applications and progress related to preclinical small-molecule drug development.
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     DeepSeek: From probabilistic generation to causal reasoning
    ZHAO Gejian, ZHANG Xinpeng
    Chinese Journal of Nature    2025, 47 (2): 79-84.   DOI: 10.3969/j.issn.0253-9608.2025.02.001
    Abstract2285)      PDF(pc) (1555KB)(3798)       Save
     The emergence of DeepSeek R1 marks a historic paradigm shift in artificial intelligence research. This groundbreaking achievement overturns the long-held dogma of traditional AI systems reliant on probabilistic generation and pattern matching. Through the deep integration of chain-of-thought and reinforcement learning, it pioneers industrial-scale AI reasoning capabilities for the first time. Its innovative reasoning architecture not only dramatically reduces the cost of training specialized AI models but also demonstrates human-like chain-of-thought characteristics in complex tasks such as mathematical proofs and logical reasoning, driving a profound transformation from probabilistic generation to causal reasoning and ushering in a new era of AI technological development. This paper traces the evolutionary trajectory of the DeepSeek model series, highlights key innovations in its chain-of thought framework and model architecture, and concludes with a discussion on the safety implications of its chain-of-thought.
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