Abstract: Ten years ago, the International Human Genome Project spent 3 billion dollars for more than a decade to complete the initial draft of the human genome. It was reasonable to consider that the scientists can draw the Map of Life and the life science stepped into postgenome era. In the first postgenome decade, on the one hand, the success of HGP have generated huge advance in biology science; on the other hand, the genomic medicine was not developed and the critics argued that genomics industry was a “genomics bubble”. Looking back over the past decade of human genomics, a retrospective review on developments and challenges of modern life science maybe promise insight into life science in postgenomic era.

Key words:  life science, postgenomic era, human genome, personalized medicine, genomewide association, system biology, Terahertz wave, magnetically ordered structure, spin wave, coherent control