中文

Chinese Journal of Nature ›› 2024, Vol. 46 ›› Issue (4): 306-316.doi: 10.3969/j.issn.0253-9608.2023.04.016

• Progress • Previous Articles    

Pathological mechanism and treatment methods of heart failure with preserved ejection fraction#br#

SONG Jiaxin①, SHEN Shutong②, ZHOU Qiulian①, GAO Juan①③   

  1. ① School of Life Science, Shanghai Engineering Research Center of Organ Repair, Shanghai University, Shanghai 200444, China; ② Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China; ③ School of Medicine, Shanghai Engineering Research Center of Organ Repair, Shanghai University, Shanghai 200444, China
  • Received:2023-01-26 Online:2024-08-21 Published:2024-08-21

PDF

1533

Abstract: Heart failure with preserved ejection fraction (HFpEF) affects about half of all patients with heart failure worldwide. The prevalence rate continues to grow with aging population year by year, while HFpEF has a high mortality rate. However, the pathogenesis of HFpEF is complex, and there is still lack of effective treatment. With the research progress in recent years, this review aims to elaborate and discuss the pathological mechanism of HFpEF and current treatment methods, providing an insight into developing novel therapeutic strategies for improving HFpEF.