中文

Chinese Journal of Nature ›› 2022, Vol. 44 ›› Issue (2): 109-116.doi: 10.3969/j.issn.0253-9608.2022.02.005

• SPECIAL ISSUE FOR BIOMEDICINE • Previous Articles     Next Articles

Advances of mitochondrial transplantation for myocardial ischemia

CHEN Hang① , HU Qinfeng② , LIN Li① , LIU Jianwen① , CHEN Kanghui① , CHEN Zhaoyang①   

  1. ①Heart Center of Fujian Province, Union Hospital, Fujian Medical University, Fuzhou 350001, China；②Institute of Biomedical
    Science, Fudan University, Shanghai 200032, China
  • Received:2021-10-14 Online:2022-04-25 Published:2022-05-05

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Abstract: Mitochondria are important organelles that provide energy to cells and regulate cell signaling and growth. The development  of many diseases is accompanied by abnormal mitochondrial function. Mitochondrial transplantation is a potential therapy for critical  diseases, especially ischemic diseases. From the perspective of mitochondrial transplantation therapy for myocardial ischemia, this article briefly reviews the effectiveness, mechanism and limitations of mitochondrial transplantation aiming to shed new light on the development of mitochondrial transplantation therapy.