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Please wait a minute... For Selected: Download Citations EndNote Ris BibTeX Toggle Thumbnails Select The development of metal–organic frameworks: A brief introduction to the Nobel Prize in Chemistry 2025 ZHANG Jiaqi, ZHANG Yuebiao Chinese Journal of Nature    2025, 47 (6): 461-468.   DOI: 10.3969/j.issn.0253-9608.2025.06.006 Abstract （95）      PDF（pc） （3779KB）（66）       Knowledge map    Save The Royal Swedish Academy of Sciences has decided to award Susumu Kitagawa, Rich ard Robson, and Omar M. Yaghi the Nobel Prize in Chemistry 2025, for the development of metal–organic frameworks. The development history, typical works and future prospects of metal–organic frameworks were briefly introduced in this article. Related Articles | Metrics | Comments（0） Select Computational protein design and structure prediction BIAN Yuemin Chinese Journal of Nature    2024, 46 (6): 429-434.   DOI: 10.3969/j.issn.0253-9608.2024.06.005 Abstract （5864）      PDF（pc） （2074KB）（1058）       Knowledge map    Save The 2024 Nobel Prize in Chemistry was awarded to three scientists — David Baker, Demis Hassabis, and John M. Jumper — for their groundbreaking contributions to the design and prediction of protein structures. This article highlights their work, offering an overview of the scientific background behind protein design and prediction in computational structural biology, the key historical challenges in the field, and how this breakthrough evolved. It also explores the far-reaching implications of their achievements for the future. Related Articles | Metrics | Comments（0） Select The discovery and innovations of quantum dots: Scientific spirit beyond the Nobel Prize in Chemistry ZHONG Haizheng, LIU Xiaoli Chinese Journal of Nature    2023, 45 (6): 417-422.   DOI: 10.3969/j.issn.0253-9608.2023.06.003 Abstract （7212）      PDF（pc） （1261KB）（2653）       Knowledge map    Save 2023 Nobel Prize in Chemistry awarded to three scientists for exploring the nanoworld. Moungi G. Bawendi, Louis E. Brus and Alexei I. Ekimov developed and discovered quantum dots, particles whose sizes govern their properties. In this paper, we tried to describe the discovery and innovations of quantum dots as well as the scientific spirit of the researchers during the developments of quantum dots. Reference | Related Articles | Metrics | Comments（0） Select The development of click chemistry and bioorthogonal chemistry: A brief introduction to the Nobel Prize in Chemistry 2022 LI Suhua Chinese Journal of Nature    2022, 44 (6): 432-442.   DOI: 10.3969/j.issn.0253-9608.2022.06.003 Abstract （2191）      PDF（pc） （3216KB）（2078）       Knowledge map    Save The Nobel Prize in Chemistry 2022 was awarded to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless for the development of click chemistry and bioorthogonal chemistry. The development history, typical works and key contributors in this area were briefly introduced in this article. Reference | Related Articles | Metrics | Comments（0） Select Contributions of Chinese chemists to asymmetric organocatalysis awarded Nobel Prize in Chemistry 2021 GAO Wenchao, JIANG Xuefeng Chinese Journal of Nature    2021, 43 (6): 430-440.   DOI: 10.3969/j.issn.0253-9608.2021 Abstract （2788）      PDF（pc） （3572KB）（1949）       Knowledge map    Save  The Nobel Prize in Chemistry 2021 returned to the basis of chemistry—synthetic chemistry, and was awarded to Benjamin List and David W. C. MacMillan for the development of asymmetric organocatalysis. This concept was formed and developed in the beginning of 21st century, and many Chinese chemists had been involved in this area. This paper was dedicated to the Chinese chemists, who contributed much thoughts and breakthrough in the area of organocatalysis in the last two decades. Reference | Related Articles | Metrics | Comments（0） Select CRISPR/Cas9, a new era of genome editing: A brief introduction to the Nobel Prize in Chemistry 2020 JIANG Yanhong, WU Yuxuan Chinese Journal of Nature    2020, 42 (6): 456-462.   DOI: 10.3969/j.issn.0253-9608.2020.06.004 Abstract （4266）      PDF（pc） （1177KB）（3448）       Knowledge map    Save  The 2020 Nobel Prize in Chemistry was awarded to two scientists for their discoveries of CRISPR/Cas9 gene editing and its molecular mechanisms. The CRISPR/Cas9 gene editing technology is regarded as one of the most important biological discoveries in the 21st century. Their discovery has led to widespread applications of the CRISPR-Cas9 system as a powerful and versatile tool in genome editing. Here, the development and application of the CRISPR/Cas9 gene editing technology and the contributions of scientists are introduced. Related Articles | Metrics | Comments（0） Select Three “godfathers” of lithium battery win the 2019 Nobel Prize in Chemistry LIU Yang, LIU Wenbo, ZHENG Feng, YAN Wei, ZHANG Jiujun Chinese Journal of Nature    2019, 41 (6): 407-413.   DOI: 10.3969/j.issn.0253-9608.2019.06.003 Abstract （2965）      PDF（pc） （4719KB）（1111）       Knowledge map    Save To enjoy the convenience of mobile phones, cameras, laptops, electromobiles, etc. in the rapid developing society, efficient energy storage are desired to power them. As one type of the efficient energy storage technologies, lithium battery with high battery voltage and high energy density, which has already contributed to improving our lives, will continue to do so in the years to come. The 2019 Nobel Prize in Chemistry has been awarded to three scientists in lithium battery. The reputation for the three “godfathers” is deserved, and it is also a spur to further development of lithium batteries. Related Articles | Metrics | Comments（0） Select Directed evolution and phage display: biological methods open up a new era of Chemistry——A brief introduction to the Nobel Prize in Chemistry 2018 GUO Xiaoqiang Chinese Journal of Nature    2018, 40 (6): 411-419.   DOI: 10.3969/j.issn.0253-9608.2018.06.004 Abstract （2200）      PDF（pc） （4312KB）（3429）       Knowledge map    Save Evolution is an important power for the diversity of life. The directed evolution of enzymes was first conducted by Frances Arnold in 1993. Enzymes produced through directed evolution are used to manufacture everything from biofuels to pharmaceuticals. The phage display, which can be used to express protein on the surface of the phage, was first developed by George Smith in 1985. The antibody was first produced with phage display by Gregory Winter in 1990. Adalimumab, the human antibody based on phage display, was approved in 2002 and then widely used in the treatment of various immune diseases. So, the directed evolution of enzymes and the phage display of antibodies have brought the greatest benefit to humankind and laid the foundation for future chemical revolution. The three scientists, Frances Arnold, George Smith and Gregory Winter, shared the Nobel Prize in Chemistry 2018 for their groundbreaking discoveries. Here, the invention and application of the methods and the contributions of scientists are introduced. Related Articles | Metrics | Comments（0） Select Cryo-EM in the past 40 years: A brief introduction to the Nobel Prize in Chemistry 2017 LI Chengmin Chinese Journal of Nature    2017, 39 (6): 417-426.   DOI: 10.3969/j.issn.0253-9608.2017.06.004 Abstract （1110）      PDF（pc） （2665KB）（2052）       Knowledge map    Save Electron microscopes have a high resolving power to reveal the details of the micro world and are used to investigate the ultrastructure of a wide range of biological specimens. However, they were long believed to not suitable for imaging biological specimens to achieve high resolution structures, because the powerful electron beam would destroy biological material and some other challenges, until the advent of cryo-electron microscopy. In this paper, we briefly reviewed the history and methodological development of electron microscopy and cryo-electron microscopy in biological specimens. Related Articles | Metrics | Comments（0） Select The tiniest machine in the world: A brief introduction to the Nobel Prize in Chemistry 2016 GU Jun, SUN Yuren, GONG Hegui Chinese Journal of Nature    2016, 38 (6): 420-428.   DOI: 10.3969/j.issn.0253-9608.2016.06.005 Abstract （734）      PDF（pc） （3602KB）（2513）       Knowledge map    Save The Royal Swedish Academy of Sciences decided to award Jean-Pierre Sauvage, J. Fraser Stoddart and Bernard L. Feringa the Nobel Prize in Chemistry 2016 for the design and synthesis of the molecular machines. In this article, we mainly introduced the concept of molecular machine and the achievement of the three scientists. Finally, the current problems and the challenges for future research were presented in this new field. Related Articles | Metrics | Comments（0） Select DNA-repair crew won the Nobel Prize in Chemistry 2015 WANG Jing, PENG Bin, XU Xingzhi Chinese Journal of Nature    2015, 37 (6): 418-423.   DOI: 10.3969/j.issn.0253-9608.2015.06.004 Abstract （1000）      PDF（pc） （2556KB）（587）       Knowledge map    Save  The Nobel Prize in Chemistry 2015 was awarded jointly to Tomas Lindahl, Paul Modrich and Aziz Sancar for having mapped and explained how the cell repairs its DNA and safeguards the genetic information. In this overview, we brie?y introduced  research achievements of the laureates and the link between DNA-repair and etiology, development, diagnosis, therapy, and the prevention of human diseases, cancer in particular. Related Articles | Metrics | Comments（0） Select Super-resolution fluorescent microscopy: A brief introduction to the Nobel Prize in#br# Chemistry 2014 JI Wei;XU Tao;LIU Bei Chinese Journal of Nature    2014, 36 (6): 404-408.   Abstract （975）      PDF（pc） （1504KB）（2496）       Knowledge map    Save Super-resolution fluorescent microscopy becomes a powerful tool for biomedical research, and extent the application of fluorescent microscopy to a brand new level. The Royal Swedish Academy of Sciences decided to award Erik Betzig, Stefan W. Hell and W. E. Moerner the Nobel Prize in Chemistry 2014 for the development of super-resolution fluorescence microscopy. Their award proved the importance of this multidisciplinary field consist of chemistry, biology and physics. In this article, we briefly introduced the historical background of super-resolution imaging, and dissect the born and development of each techniques. Finally, the current problems and the challenges for future research were presented. Related Articles | Metrics | Comments（0） Select Computer molecular modeling: A brief introduction to the Nobel Prize in Chemistry 2013 TANG Yun; LI Wei-Hua; Sheng Ya-Yun Chinese Journal of Nature    2013, 35 (6): 408-415.   Abstract （985）      PDF（pc） （1643KB）（1016）       Knowledge map    Save Computer molecular modeling has been widely used in solving complex chemical and biological problems, such as drug design and materials design, since it was developed 50 years ago. The Nobel Prize in Chemistry 2013 was awarded to Martin Karplus, Michael Levitt and Arieh Warshel for developing the multiscale models of complex chemical systems, which demonstrated that for today chemical experiment on computers is the same important as that on test tubes, and theory and practice should cross-fertilize each other to solve complex problems. In this article, we briefly reviewed the basic concept, history of methodological development, and applications of computer molecular modeling. A future perspective was also provided. Related Articles | Metrics | Comments（0） Select G Protein Coupled Receptors, the Magic Molecules with Seven Transmembrane Helices: A Brief Introduction to the Nobel Prize in Chemistry LU Wei-Zhen, WU Bei-Li, ZHAO Jiang Chinese Journal of Nature    2012, 34 (6): 337-343.   Abstract （2241）      PDF（pc） （721KB）（3119）       Knowledge map    Save G protein coupled receptors are the largest and the most important protein family in human genome, which involved in almost all of the living activities. The gene cloning, functional studies and structural determination of these receptors shed a new light on understanding the physiological regulation and the pathogenicity and treatment of almost all the human diseases. The Nobel Prize had issued to related research for 9 times, and in 2012, the Nobel Prize in Chemistry was issued to two American scientists, Robert J. Lefkowitz and Brian K. Kobilka, for their extraordinary work on this area, especially on β2 adrenergic receptors. In this paper, we briefly reviewed the research progresses of G protein coupled receptors in the past, their unique 7 transmembrane architecture, activation mechanism and their future trends.  Related Articles | Metrics | Comments（0） Cited: Baidu(2) Select Quasi-periodic Crystals：Exotic but Common —A Brief Introduction to the Nobel Prize in Chemistry 2011 DONG Chuang, WANG Ying-min, QIANG Jian-bing, WANG Qing Chinese Journal of Nature    2011, 33 (6): 322-327.   DOI: 10.3969/j.issn.0253-9608.2011.06.003 Abstract （12684）      PDF（pc） （1428KB）（1270）       Knowledge map    Save Quasicrystals are solid phases having long-range quasiperiodic translational order and non-crystallographic rotational symmetry. The discovery of quasicrystals has brought about a paradigm shift in the understanding of the structure of matters. The influences of it, which is in obedience to no previously thought-out plan, on the way of thinking of Human beings are enormous, profound and lasting. Daniel Shechtman won the Nobel Prize for Chemistry in 2011 for his discovery of quasicrystals. The past and the current status of quasicrystal research are shortly reviewed in this paper, in which the outstanding scientific contributions of Chinese scientists are introduced. Related Articles | Metrics | Comments（0） Select PalladiumCatalyzed CrossCoupling Reactions:A Brief Introduction to the Nobel Prize in Chemistry 2010 XIAO Tang-Xin;LIU Li Jiang-Ju-Chi;WANG Le-Yong Chinese Journal of Nature    2010, 32 (6): 332-337.   Abstract （1822）            Knowledge map    Save On Oct 6th, 2010, the Royal Swedish Academy of Sciences announced that the Nobel Prize in chemistry for 2010 was awarded jointly to an American scientist Richard F. Heck and two Japanese scientists Eiichi Negishi and Akira Suzuki for their great contributions to palladiumcatalyzed crosscoupling. It provides one of the most sophisticated tools available to chemists to create complicated organic molecules. This tool has been widely used in pharmaceuticals, electronics industry, and advanced materials. A brief introduction for palladiumcatalyzed crosscoupling was presented in this paper. Related Articles | Metrics | Comments（0） Select The Great Journey of the Ribosome Research: 2009’s Nobel Prize in Chemistry LING Zhi-Xiang;LIU Wang-Yi Chinese Journal of Nature    2009, 31 (6): 337-.   Abstract （1944）            Knowledge map    Save ]The 2009 Nobel Prize in Chemistry was awarded to two American scientists Venkatraman Ramakrishnan, Thomas A. Steitz and the Israel female scientist Ada E. Yonath for their Xray diffraction analysis of the structure and function of ribosome. Their work showed the ribosome at atomic resolution and allowed the construction of a detailed threedimensional model of ribosome.The bacterial ribosome (70S) consists of a small (30S) and a large (50S) subunit. The 30S subunit is composed of 21 distinct proteins and a molecule of 16S rRNA. The 50S subunit is composed of 34 different proteins, a molecule of 23S rRNA and a molecule of 5S rRNA. The eukaryotic ribosomes are larger and more complex than those from prokaryotes. Various proteins synthesized in ribosomes in turn control the chemistry in all living organisms. As ribosomes are crucial to life, they are also a major target for antibiotics and RIP. Related Articles | Metrics | Comments（0） Select Three landmarks during the research of the green fluorescent protein (GFP): a brief introduction to the 2008 Nobel Prize in Chemistry CUI Zhi-fang;ZOU Yu-hong;JI Ai-yun Chinese Journal of Nature    2008, 30 (6): 324-328.   Abstract （2217）            Knowledge map    Save American scientists Osamu Shimomura, Martin Chalfie and Roger Y. Tsien are jointly awarded the 2008 Nobel Prize in chemistry on 8 October, 2008 for their extraordinary discovery and reconstruction of the green fluorescent protein (GFP). The research history and the application field of GFP were discussed in the paper. Related Articles | Metrics | Comments（0） Select The Development of Modern Surface Chemistry:Brief Introduction to the Nobel Prize in Chemistry 2007 MA Xiu-Fang;LI Wei-Xue;DENG Huiqiu Chinese Journal of Nature    2007, 29 (6): 353-357.   Abstract （1889）            Knowledge map    Save Related Articles | Metrics | Comments（0） Select Molecular Mechanism of Eukaryotic Transcription: a Brief Introduction to the Nobel Prize in Chemistry 2006 MENG Xiang-zong;XU Zheng-kai;SONG Ren-tao Chinese Journal of Nature    2006, 28 (6): 329-332.   Abstract （1889）            Knowledge map    Save Related Articles | Metrics | Comments（0） Cited: Baidu(2)