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    25 December 2018, Volume 40 Issue 6
    Invited Special Paper
    How plants see
    DENG Xingwang
    2018, 40(6):  391-399.  doi:10.3969/j.issn.0253-9608.2018.06.001
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    Animals and plants were formed in their present states during the long-term evolution of life on the earth. Generally, animals can perceive light by their eyes, and then convert the information from the light to electrical impulses for their brains to interpret what they have seen and how to react. Furthermore, animals can move autonomously according to the changed environments or to their own requirement. Plants are distinct from animals in their development and their lifestyle, they do not have eyes and brain, and they live in one place throughout the life without the ability to move by themselves. However, plants have their own advantages. They have exuberant vitality and strong fertility, and can live up to several thousand even tens of thousands years, which is never achieved for animals. Besides making the earth rich and colorful, plants also provide food for animal life. Although they can not move, plant can make sense of the
    complex world, and there are competition and cooperation between different plant species. Magically, without eyes, plant can also see the light including those wavelength of light which we can not see, and can response to different light period.

    Brief Introduction of Nobel Prize
    From chirped pulse amplification to high field laser physics: A brief introduction to the Nobel Prize in Physics 2018
    LENG Yuxin
    2018, 40(6):  400-406.  doi:10.3969/j.issn.0253-9608.2018.06.002
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    In 1985, Donna Strickland and Gérard Mourou published a paper about the invention of chirped pulse amplification (CPA) conception, a milestone of high peak power laser development, which generated the ultra-intense and ultra-short laser and high field laser physics. Now, the peak power of PW even 10 PW is possible based on CPA, which is regarded as “their work will affect research on everything from fusion to astrophysics”. Therefore, due to the invention of CPA, Prof. Gérard Mourou and Prof. Donna Strickland won the Nobel Prize in Physics 2018. This paper will give a brief introduction about the CPA technology, and the significance about Prof. Gérard Mourou and Prof. Donna Strickland’s invention with the recent progresses of ultra-intense and ultra-short laser, related high field physics and Shanghai Superintense Ultrafast Laser Facility (SULF) in State Key Laboratory of High Field Laser Physics in SIOM.

    History of Natural Science
    Tumors will be cured by immune therapy:A brief introduction to the Nobel Prize in physiology or medicine 2018
    LI Dan, WANG Xiaoxia, LI Bin
    2018, 40(6):  407-410.  doi:10.3969/j.issn.0253-9608.2018.06.003
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    In 2018, the Nobel Prize in physiology or medicine was awarded to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulation. This article reviews the process of immune checkpoints discovered by the two scientists from the mechanism to clinical trials. The immune therapy gives human an opportunity to cure tumor.

    Brief Introduction of Nobel Prize
    Directed evolution and phage display: biological methods open up a new era of Chemistry——A brief introduction to the Nobel Prize in Chemistry 2018
    GUO Xiaoqiang
    2018, 40(6):  411-419.  doi:10.3969/j.issn.0253-9608.2018.06.004
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    Evolution is an important power for the diversity of life. The directed evolution of enzymes was first conducted by Frances Arnold in 1993. Enzymes produced through directed evolution are used to manufacture everything from biofuels to pharmaceuticals. The phage display, which can be used to express protein on the surface of the phage, was first developed by George Smith in 1985. The antibody was first produced with phage display by Gregory Winter in 1990. Adalimumab, the human antibody based on phage display, was approved in 2002 and then widely used in the treatment of various immune diseases. So, the directed evolution of enzymes and the phage display of antibodies have brought the greatest benefit to humankind and laid the foundation for future
    chemical revolution. The three scientists, Frances Arnold, George Smith and Gregory Winter, shared the Nobel Prize in Chemistry 2018 for their groundbreaking discoveries. Here, the invention and application of the methods and the contributions of scientists are introduced.

    Progress
    From carbon to hydrogen energy: yesterday, today and tomorrow
    BASHIR Sajid,ZHEN Qiang,LI Rong,LI Cuixia,LIU Jingbo Louise
    2018, 40(6):  420-426.  doi:10.3969/j.issn.0253-9608.2018.06.005
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    This paper briefly outlined the development of the modern energy, with a focus on hydrogen as alternative fuels. Three key fields, production, storage and application are discussed. Being high energy carrier, the hydrogen can provide high energy density as a fuel, with zero or near-zero emission of carbon to the atmosphere. The authors found that the de-centralized hydrogen technique can improve the velocity and mileage of a fuel-cell-driven model car by more than 30%.

     

    Future development trend of control technology for marine transportation platform
    YANG Yi, JIANG Tao, KE Jun, CHEN Huizi
    2018, 40(6):  427-437.  doi:10.3969/j.issn.0253-9608.2018.06.006
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    As a way of recognizing, developing and utilizing the ocean, marine transportation platform is widely used in marine biological observation, oil and gas exploitation and other fields. However, the platforms generally have such problems as large inertia, highly nonlinear. In this paper, we focus on the actual control requirements of platforms. The importance and possibility of developing control techniques under the condition of bad sea condition and complex multi task are discussed. At the same time, we put forward to the research direction that should be developed in the future of the function and control technology for the marine transportation platform. Finally, we put forward to the roadmap of control technology development for marine transportation platform basedon a series of policies.

    Focusing on Nav1.7 channel: moving towards pain precision medicine
    LIU Yamei, LIU Yushuang, ZHANG Jingliang, WANG Jing, LI Min, CHEN Fuxue,YANG Yang
    2018, 40(6):  435-444.  doi:10.3969/j.issn.0253-9608.2018.06.007
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    Chronic pain is a global unmet medical need. Most available treatments are only partially effective or have side effects that limit their utilities. Rapid progress has been made to elucidate the contributions of specific genes to the chronic pain, suggesting possibility to advance pain pharmacotherapy. Focusing on voltage-gated sodium channel Nav1.7 as an example, this article reviews recent progress in painpharmacogenomics, new development of disease models using patient-specific induced pluripotent stem cells (iPSCs) derived sensory neurons, as well as advances in structural modeling and electrophysiology recording.These new approaches will hopefully transform the treatment of pain from trial-and-error toward precision pharmacotherapy.

    Natural Forum
    Reflections on the construction of the system of the Beautiful China
    DENG Wei, SONG Xueqian
    2018, 40(6):  445-450.  doi:10.3969/j.issn.0253-9608.2018.06.008
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    The concept of the Beautiful China is proposed as a concrete goal of the construction of national ecological civilization in China. Chinese President Xi Jinping pointed out that it is necessary to speed up the reform of the ecological civilization system, and the processes of building the Beautiful China must be integrated into economic, political, cultural and social constructions. This fully indicates the national noble and advanced thought of sustainable development. Building the Beautiful China is a complete system which constitutes of natural systems, economic systems and social systems, and it is promoted by culture and technology. Only when the connotation of building the Beautiful China being interpreted profoundly, can the system be constructed scientifically, the targeted policy must be implemented precisely, the construction be promoted orderly in time and space and efficiently, and finally the great
    resurge of the Chinese nation be realized.

    Paleoclimate implication for the global warming and its uncertainties
    WEI Junxiao, CEN Kuang
    2018, 40(6):  451-458.  doi:10.3969/j.issn.0253-9608.2018.06.009
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    Main factors that affect global warming are clarified to objectively evaluate the current causes and the uncertainties associated with global warming. Various climatic parameters, such as extreme weather events, paleo-atmospheric composition, and paleo-temperature during the “deep time” (pre-Quaternary) period as well as seven uncertainties with respect to the current global warming, are analyzed. It is necessary to analyze the climate change that has occurred since the Quaternary, especially the current global warming, from a holistic geological history process. In addition, the interaction among the atmosphere, hydrosphere, biosphere, pedosphere, and lithosphere should be considered. The mutual coupling, cause-and-effect feedback, and multi-angle and multi-disciplinary techniques should be employed to analyze global warming. Furthermore, the solar activities, earth orbit changes, and other such extraterrestrial factors should be considered. Although human activities have a major impact on global warming, the contribution of natural factors should be quantified. Finally, various countermeasures and suggestions for CO2 reduction and for responding to the global warming situation in China are presented, and the importance of upholding the principle of “common but differentiated responsibilities” while engaging in international climate negotiations is highlighted.

    Science Review
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