自然杂志 ›› 2018, Vol. 40 ›› Issue (2): 131-135.doi: 10.3969/j.issn.0253-9608.2018.02.007

• 科技进展 • 上一篇    下一篇

水稻“抗癌”新因子bsr-d1

李伟滔,朱紫薇,尹俊杰,贺闽,王静,朱孝波,陈学伟   

  1. 四川农业大学水稻研究所,成都 611130
  • 收稿日期:2017-09-06 出版日期:2018-04-25 发布日期:2018-04-23

Novel allele bsr-d1 conferring broad-spectrum blast resistance

LI Weitao, ZHU Ziwei, YIN Junjie, HE Min, WANG Jing, ZHU Xiaobo, CHEN Xuewei   

  1. Rice Research Institute, Sichuan Agricultural University, Chengdu 611130, China
  • Received:2017-09-06 Online:2018-04-25 Published:2018-04-23

摘要:

稻瘟病被称为水稻“癌症”,严重危害水稻的产量和品质,应用广谱持久抗稻瘟病基因是抵御稻瘟病侵害最有效的方法之一。利用全基因组关联分析(genome-wide association study,GWAS)结合重组自交系遗传群体共相关分析,从广谱持久高抗稻瘟病水稻材料“地谷”中鉴定并获得了一个广谱抗病遗传位点bsr-d1bsr-d1通过调控过氧化氢酶基因的表达调节H2O2的积累,从而影响水稻的稻瘟病抗性。bsr-d1提高稻瘟病抗性的同时,对水稻产量和品质影响不明显,因此在水稻抗病育种中具有广阔的应用前景。

关键词: 稻瘟病, 全基因组关联分析, 广谱抗病, 水稻

Abstract:

Blast, called “rice cancer”, is one of the severe diseases and seriously affects the yields and quality of rice. Genetic improvement using broad-spectrum resistance genes is one of the most effective methods to control rice blast. Using a strategy combined with genome-wide association study (GWAS) and correlation analysis of recombinant inbred lines, we identified a novel blast resistance allele, bsr-d1, from rice variety Digu. The bsr-d1 enhances blast resistance by regulating accumulation of H2O2 that relied on the expression of peroxidase genes. This allele, bsr-d1 conferred broad-spectrum resistance against blast without obvious penalty on rice yields or quality. Thus, bsr-d1 offers an alternative strategy for breeding durable resistance in rice.