自然杂志 ›› 2020, Vol. 42 ›› Issue (2): 116-124.doi: 10.3969/j.issn.0253-9608.2020.02.007

• 专题综述 • 上一篇    下一篇

射血分数中间值心力衰竭的研究进展与展望

朱凯媛,鄢春喜,徐大春   

  1. ①江苏省启东市人民医院/南通大学附属启东医院心内科,江苏 南通 226600; ②同济大学附属第十人民医院 心内科,上海 200072
  • 收稿日期:2020-02-05 出版日期:2020-04-25 发布日期:2020-04-18
  • 作者简介:徐大春,通信作者,研究方向:心力衰竭发生的分子机制及心脏功能再生。

Advance research and future directions in the heart failure with mid-range ejection fraction#br#

  1. ①Department of Cardiology, Qidong people’s Hospital/Affiliated Qidong Hospital of Nantong University, Nantong 226000, Jiangsu Province, China; ②Department of Cardiology, The Tenth People’s Hospital of Tongji University, Shanghai 200072, China
  • Received:2020-02-05 Online:2020-04-25 Published:2020-04-18

摘要: 文章综述了射血分数中间值心力衰竭患者的流行病学、病理生理学、临床表现和预后等特点,以及这些特征与已更深入研究的其他心力衰竭组的比较。目前推荐的治疗方法侧重于积极的共病管理,而文章总结并确定了有益的潜在信号研究,未来的研究不仅需要更好地描述心衰人群,还需要确定有效的管理策略,以减少心衰患者高心血管发病率和死亡率。

关键词: 心力衰竭, 射血分数中间值心力衰竭, 左室射血分数

Abstract: We summarize what is known about the clinical epidemiology, pathophysiology, and prognosis for patients with HFmrEF and how these features compare with the more well-studied HF groups. Although recommended treatments currently focus on aggressive management of comorbidities, we summarize the studies that identify a potential signal for beneficial therapies. Future studies are needed to not only better characterize the HF population but also determine effective management strategies to reduce the high cardiovascular morbidity and mortality burden on this phenotype of patients with HF.

Key words: heart failure, HFmrEF, LVEF