2020年的诺贝尔化学奖颁给了两位研究CRISPR/Cas9的科学家，以表彰她们对新一代基因编辑技术开发及分子机制 研究所做出的贡献。CRISPR/Cas9基因编辑技术一经诞生就被视为21世纪最为重要的生物发现之一。由于其稳定高效， CRISPR/Cas9技术已经成为基因组编辑的强大工具，在生命科学的各个领域都展现出广阔的应用前景，并且也为疾病的临 床治疗提供了新策略。文章回顾了两位科学家对CRISPR/Cas9基因编辑系统开发的重要贡献，同时也对基因编辑技术的发 展及应用进行了简单介绍。

 The 2020 Nobel Prize in Chemistry was awarded to two scientists for their discoveries of CRISPR/Cas9 gene editing and its molecular mechanisms. The CRISPR/Cas9 gene editing technology is regarded as one of the most important biological discoveries in the 21st century. Their discovery has led to widespread applications of the CRISPR-Cas9 system as a powerful and versatile tool in genome editing. Here, the development and application of the CRISPR/Cas9 gene editing technology and the contributions of scientists are introduced.