Chinese Journal of Nature ›› 2021, Vol. 43 ›› Issue (6): 391-399.doi: 10.3969/j.issn.0253-9608.2021.06.001

• Special Issue for Advanced Immunochemical Studies •     Next Articles

Advances in research on tumor immunotherapy

LI Long①③ , XIE Chengying , ZHENG Mingyue , JIANG Hualiang①②   

  1. ①Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai 201210, China; ②Drug Discovery
    & Development Center, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; ③Center for
    Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China
  • Received:2021-06-01 Online:2021-10-25 Published:2021-10-25

Abstract: Tumor immunotherapy can control and kill tumor cells by stimulating or restoring the immune system. It is another effective treatment after surgery, radiotherapy, chemotherapy and targeted therapy. A variety of emerging tumor immunotherapies
are being applied in clinical research and demonstrate the potential of powerful treatment, benefiting from the rapid development
of multiple-subjects such as immunology and tumor biology. At present, clinical immunotherapeutic strategies for cancer include
therapeutic monoclonal antibody immunotherapy, immune checkpoint inhibitor therapy, adoptive cell therapy, oncolytic virus therapy, and tumor vaccine. This paper reviews the development of tumor immunotherapy, and analyzes the latest research progress and futureprospects, in order to provide reference for drug research and development in tumor immunotherapy.