Abstract: The Earth is ca. 4 600 Ma old up to now. 545 Ma is a key boundary mark. The epoch greater than 545 Ma is called Precambrian Era, time range of which is about 4 000 Ma long. The epoch of 545 Ma is termed Phanerozoic Era. Cambrian is the first geological period of Phanerozoic Era. The 80%~90 % volume of continental crust was formed in Precambrian. Oldage continent crust records complicated and supernatural geotectonic history, and contains abundant mineral resources with enormous reserves. Precambrian geology is a branch of Earth sciences that study geological process and ending in precambrian, including early continent forming and evolving.

Key words: Gene targeting Functional gene Animal model Embryonic Stem Cell, Earth, continental crust, originate and evolve, Precambrian geology