中文

Chinese Journal of Nature ›› 2013, Vol. 35 ›› Issue (6): 422-430.

• Review Article • Previous Articles     Next Articles

Mouse，the “evergreen tree” in the model organisms

KUANG Ying①, FEI Jian②   

  1. ①Professor，Shanghai Research Center for Model Organisms, Shanghai 201210, China ②Professor, Shanghai Research Center for Model Organisms, Shanghai 201210, China; School of Life Sciences and Technology, Tongji University, Shanghai 200092, China
  • Received:2013-10-09 Revised:2013-11-09 Online:2013-12-25 Published:2013-12-25

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Abstract: The origin of laboratory mice and their application in life sciences research were reviewed, including spontaneous mutant mouse models and genetically modified mouse models. The new technologies to develop genetically modified mice were also introduced.

Key words: mouse, model organism, life sciences