Chinese Journal of Nature ›› 2018, Vol. 40 ›› Issue (6): 407-410.doi: 10.3969/j.issn.0253-9608.2018.06.003

• History of Natural Science • Previous Articles     Next Articles

Tumors will be cured by immune therapy:A brief introduction to the Nobel Prize in physiology or medicine 2018

LI Dan, WANG Xiaoxia, LI Bin   

  1. Shanghai Institute of Immunology, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China
  • Received:2018-12-03 Online:2018-12-25 Published:2018-12-21

Abstract:

In 2018, the Nobel Prize in physiology or medicine was awarded to James P. Allison and Tasuku Honjo for their discovery of cancer therapy by inhibition of negative immune regulation. This article reviews the process of immune checkpoints discovered by the two scientists from the mechanism to clinical trials. The immune therapy gives human an opportunity to cure tumor.