自然杂志 ›› 2023, Vol. 45 ›› Issue (5): 389-393.doi: 10.3969/j.issn.0253-9608.2023.04.015

• 科技进展 • 上一篇    下一篇

三叉神经痛的分类及临床诊疗

赵琳琳,汪煜楠,张惊宇   

  1. 哈尔滨医科大学 附属第四医院神经内科,哈尔滨 150001 
  • 收稿日期:2023-01-19 出版日期:2023-10-25 发布日期:2023-10-25
  • 通讯作者: 赵琳琳,研究方向:脑血管病的诊断与治疗。 张惊宇,研究方向:脑血管病的诊断与治疗
  • 基金资助:
    国家自然科学基金面上项目(62272138)、 横向课题项目“外泌体对脑缺血再灌注损伤的作用及机制研究”(HX2020-12)

Research in classification, clinical diagnosis and treatment of trigeminal neuralgia

  1. Department of Neurology, the Fourth Affiliated Hospital of Harbin Medical University, Harbin 150001, China
  • Received:2023-01-19 Online:2023-10-25 Published:2023-10-25

摘要: 三叉神经痛是一种发生于头面部三叉神经分布区域内,症状表现为骤发、骤停、闪电样、刀割样、烧灼样、顽固性、难以忍受的剧烈疼痛的疾病。其发病机制尚不明确,可能与神经病变、免疫炎症机制及离子通道相关。目前,治疗三叉神经痛仍以药物治疗为主,药物治疗无效时可考虑电生理治疗或手术治疗,包括射频热凝术、微血管减压术以及球囊压迫术等。文章综述了三叉神经痛的分类及临床诊疗的研究进展,以期为其临床尽早确诊及治疗提供新的理论基础。

关键词: 三叉神经痛, 分类, 临床诊疗

Abstract: Trigeminal neuralgia is a kind of severe pain that occurs in the distribution area of trigeminal nerve in the head and face, including sudden onset, sudden stop, lightning, knife cutting, burning, intractable and unbearable. Its pathogenesis is not clear. It is often considered that it may be related to neuropathy, immune inflammatory mechanism and ion channel, and its treatment methods are also diverse. At present, it is still dominated by drug treatment. When drug treatment is ineffective, electrophysiological therapy and surgical treatment can be considered, including radiofrequency thermocoagulation, microvascular decompression and balloon compression. This paper summarizes the classification and clinical diagnosis and treatment of trigeminal neuralgia, in order to provide the latest theoretical basis for the early clinical diagnosis and treatment of trigeminal neuralgia.