自然杂志

• 科学人物 •    下一篇

执著与美丽:多萝西•克劳福特•霍奇金的晶体人生

尹辉†,李侠   

  1. 上海交通大学 科学史与科学文化研究院,上海 200240
  • 出版日期:2025-05-23 发布日期:2025-05-23

 Perseverance and beauty: the crystal life of Dorothy Crawford Hodgkin

YIN Hui, LI Xia   

  1. School of History and Culture of Science, Shanghai Jiao Tong University, Shanghai 200240, China
  • Online:2025-05-23 Published:2025-05-23

摘要:  英国著名化学家多萝西•克劳福特•霍奇金因“运用X射线技术测定重要生化物质的结构”获得1964年诺贝尔化学奖。多萝西一生致力于X射线晶体学,成功解析了碘化胆固醇、青霉素、维生素B12和胰岛素等复杂分子的结构,对生物化学、医学等领域产生深远的影响。多萝西不仅是杰出的科学家,还是推动国际科学合作和维护世界和平的重要使者。本文通过 回顾多萝西的成长经历、科研成果以及社会活动,为科研工作者提供两点启发:一要执著探索,勇攀学术高峰;二要担起社会责任,坚守美好心灵。

关键词: 多萝西?克劳福特?霍奇金, 晶体, 诺贝尔化学奖

Abstract:  Dorothy Crawford Hodgkin, a famous British chemist, was awarded the 1964 Nobel Prize in Chemistry for “the determination of the structure of important biochemical substances by X-ray technique”. Dorothy devoted her life to X-ray crystallography and successfully analyzed the structures of complex molecules such as cholesterol iodide, penicillin, vitamin B12 and insulin, which had far-reaching impacts on the fields of biology and medicine. Dorothy was not only an outstanding scientist, but also an important messenger to promote international scientific cooperation and maintain world peace. By reviewing Dorothy’s growth experience, scientific research achievements and social activities, this article provides two inspirations for scientific researchers: firstly, they should be persistent in exploration and climb to the academic peak; secondly, they should take up social responsibility and hold fast to their beautiful hearts.

Key words:  , Dorothy Crowfoot Hodgkin, crystal, the Nobel Prize in Chemistry