自然杂志 ›› 2017, Vol. 39 ›› Issue (6): 411-416.doi: 10.3969/j.issn.0253-9608.2017.06.003

• 诺贝尔奖简介 • 上一篇    下一篇

生物钟:基因和环境决定的行为——2017年诺贝尔生理学或医学奖简介

俞强   

  1. 中国科学院上海药物研究所,上海 201203
  • 收稿日期:2017-11-22 修回日期:2017-11-30 出版日期:2017-12-25 发布日期:2017-12-26

Biological clock, the gene and environment-determined behavior: A brief introduction to the Nobel Prize in Physiology or Medicine 2017

YU Qiang   

  1. Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
  • Received:2017-11-22 Revised:2017-11-30 Online:2017-12-25 Published:2017-12-26

摘要:

2017年的诺贝尔生理学或医学奖颁给了三位研究果蝇生物钟行为的美国科学家——杰弗里 • 霍尔(Jeffrey C. Hall)、迈克尔 • 罗斯巴什(Michael Rosbash)和迈克尔?杨(Michael W. Young),奖励他们发现了决定生物钟行为的基因和这些基因产物的工作原理。生物钟,也叫生物日节律或昼夜节律(circadianrhythm),是生物以约昼夜24小时为周期的节律性行为。生物钟行为是一个在各种动植物中都普遍存在的自然现象。生物钟基因的发现和对这些基因产物工作原理的揭示对了解生命和生命的运行原理,特别是对基因、行为和环境三者之间的关系有着重要的理论意义,同时也为利用生物钟原理来解决生产活动和健康医疗中的生物学问题奠定了应用基础。

关键词: 诺贝尔奖, 生物钟, 生物节律, 基因, 行为

Abstract:

The 2017 Nobel Prize in physiology or medicine was awarded to three scientists from the United States, Jeffrey C. Hall, Michael Rosbash, and Michael W. Young, for their discoveries of genes and molecular mechanisms of the biological clock of fruit flies. The biological clock, also called circadian rhythm, is any biological process that oscillates with a period of about 24 hours. It is a common and basic phenomenon of lives in nature. The discoveries of clock genes and the elucidation of the molecular mechanisms of the clock shed lights on the understanding of the nature of life, particularly the relationships among genes, behaviors, and environments, and provide the bases for applications of the principles of the biological clock in our life.

Key words: Nobel Prize, biological clock, biological rhythm, gene, behavior