Chinese Journal of Nature ›› 2022, Vol. 44 ›› Issue (2): 103-108.doi: 10.3969/j.issn.0253-9608.2022.02.004

• SPECIAL ISSUE FOR BIOMEDICINE • Previous Articles     Next Articles

Pathogenic mechanism, prevention and treatment of doxorubicin-induced cardiotoxicity

WANG Qingwei, DING Rongjing   

  1. Peking University People's Hospital, Beijing 100044, China
  • Received:2021-12-12 Online:2022-04-25 Published:2022-05-05

Abstract: Doxorubicin can be used to treat a variety of malignant tumors, but its wide clinical application is limited by doxorubicin-induced cardiotoxicity. The pathogenic mechanism of doxorubicin-induced cardiotoxicity remains unclear, and the available evidence
for prevention and treatment is still insufficient. This article reviews the pathogenic mechanisms, prevention and treatment of
doxorubicin-induced cardiotoxicity, aiming to provide a more extensive treatment idea and laboratory evidence for further exploration
of doxorubicin-induced cardiotoxicity.