自然杂志 ›› 2009, Vol. 31 ›› Issue (2): 63-68.

• 特约专稿 •    下一篇

小虫春秋:果蝇的视觉学习记忆与认知

郭爱克①彭岳清②张柯③奚望④   

  1. ①中国科学院院士,中国科学院神经科学研究所,神经科学国家重点实验室,上海 200031; 中国科学院生物物理研究所,脑与认知科学国家重点实验室,北京 100101;②③④博士,中国科学院神经科学研究所,神经科学国家重点实验室,上海 200031
  • 收稿日期:2009-02-09 修回日期:2009-02-09 出版日期:2009-04-20 发布日期:2009-04-20

Insect Behavior: Visual Cognition in Fruit Fly

GUO Ai-ke①, PENG Yue-qin②, ZHANG Ke,③ XI Wang④   

  1. ①CAS Member, Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, CAS,Shanghai 200031, China; State Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, CAS, Beijing 100101, China; ②③④Ph.D., Institute of Neuroscience, State Key Laboratory of Neuroscience, Shanghai Institutes for Biological Sciences, CAS,Shanghai 200031, China
  • Received:2009-02-09 Revised:2009-02-09 Online:2009-04-20 Published:2009-04-20

摘要: 视觉认知是脑科学领域中的重要研究方向,是揭示 “脑是怎样工作的”,“物质的脑是如何产生精神的”的重要路径。近年来,科学家们以果蝇为模式生物,从基因脑行为认知相结合的角度,系统性地开创了果蝇的视觉“认知”研究,如学习与记忆、注意、跨模态记忆、特征提取和泛化、两难抉择、抉择的神经环路等。即使果蝇这样相对简单的脑,在很多方面都展示了令人惊奇的“理性”行为。看来,那种认为只有某些独特的唯一的脑机制才能实现人类的理性的想法是不成立的。我们期待,在探索“智与愚”的神经生物基础方面,果蝇会对我们继续有所帮助。

关键词: 果蝇, 视觉不变性, 记忆痕迹, 两难抉择, 特征抽提, 记忆协同

Abstract: Visual cognition, as one of the fundamental aspects of neurobiology, is the way to explore “How does the brain function as a whole?”“How matter becomes imagination?” Drosophila, as a model organism, shares certain features of visual cognition in common with mammals at the genetic, molecular, cellular, and even higher behavioral levels. Thus the fly brain therefore could provide a useful vehicle for exploring the neural mechanisms underlying visual cognition from a genesbrainbehavior perspective. Here, we consider mainly the higher cognitive behaviors based on learning and memory, such as visual pattern recognition, context generalization, visual  saliencebased decision, and attentionlike behavior. It seems that even fruit fly with very small brain can behave in a surprisingly rational manner under a broad range of conditions. This seems to argue against the concept that in order to behave rationally humans would have needed to evolve some unique facility. We hope that our focus on these aspects of Neuroscience  will shed light on our understanding the “brainmind” relationship.

Key words: Drosophila, visual invariant perception, visual memory trace, saliencybased decision, visual feature extraction, crossmodal interaction