基因表达调控机制——操纵子模型的确立

自然杂志 ›› 2013, Vol. 35 ›› Issue (4): 286-297.

基因表达调控机制——操纵子模型的确立

向义和

教授，清华大学物理系，北京 100084

收稿日期:2013-01-03 修回日期:2013-02-03 出版日期:2013-08-25 发布日期:2013-08-25

The establishment of genetic regulatory mechanisms—operon model

XIANG Yi-he

Professor, Department of Physics，Tsinghua University, Beijing 100084, China

Received:2013-01-03 Revised:2013-02-03 Online:2013-08-25 Published:2013-08-25

摘要/Abstract

摘要： 笔者介绍了基因表达调控机制——操纵子模型建立的过程：诱导物和阻遏物的发现及对其性质的研究；调
节基因和操纵基因的发现及对其性能的分析；操纵子模型建立和实验验证。

关键词: 诱导物, 阻遏蛋白, 调节基因, 操纵基因, 结构基因, 操纵子

Abstract: The establishment of genetic regulatory mechanisms—operon model is introduced. The key events include the discovery
of inducer, repressor, regulator gene and operator, the study of their properties, the establishment of operon model and the evidence of
experiment.

Key words: inducer, repressor, regulator gene, operator, structural gene, operon

向义和. 基因表达调控机制——操纵子模型的确立[J]. 自然杂志, 2013, 35(4): 286-297.

XIANG Yi-He. The establishment of genetic regulatory mechanisms—operon model[J]. Chinese Journal of Nature, 2013, 35(4): 286-297.