自然杂志 ›› 2018, Vol. 40 ›› Issue (4): 253-264.doi: 10.3969/j.issn.0253-9608.2018.04.004

• 专题综述 • 上一篇    下一篇

从蝾螈到克隆猴:核移植研究90周年记

秦逸人   

  1. 中国科学院生物与化学交叉研究中心,上海 201203
  • 收稿日期:2018-05-04 出版日期:2018-08-25 发布日期:2018-09-03
  • 作者简介:通信作者,研究方向:利用基因编辑技术结合干细胞开展对单基因遗传疾病的研究;利用显微操作与核移植技术开展对胚胎发育与干细胞相关问题的探讨。E-mail:yirenqin@sioc.ac.cn; yirenqin@hotmail.com

From salamander to cloned monkey: development and applications of nuclear transfer

QIN Yiren   

  1. Interdisciplinary Research Center on Biology and Chemistry, Chinese Academy of Sciences, Shanghai 201203, China
  • Received:2018-05-04 Online:2018-08-25 Published:2018-09-03

摘要:

从第一例核移植动物到第一例体细胞核移植灵长类动物,核移植研究恰好迎来90周年。在这近百年的研究历程中,核移植研究不仅回答了一系列重大科学问题,且在许多方面已投入到实际应用。文章详述了核移植研究的发展历程、实际应用及其发展现状。

关键词:  , 核移植, 90周年, 发展, 应用

Abstract:

From first nuclear transfer animals to first somatic cell nuclear transfer primates, nuclear transfer research has experienced for 90 years. During this nearly 100-year research course, it not only addressed a series of important scientific questions, but also has been put into practical applications in many aspects. Here we reviewed the developments and applications of nuclear transfer.